Francis married Emma Louise Drollinger on 25 Dec 1878 in Lee County, IA. Emma (daughter of Benjamin Wesley Drollinger and Susan Laura Wilson) was born on 25 Dec 1858 in Ft. Madison, Lee, IA; died on 6 Nov 1955 in Lee County, IA; was buried in Ft. Madison, Lee, IA. [Group Sheet] [Family Chart]

1. Benjamin Francis Holmes was born on 27 Sep 1879 in Montrose, Lee, IA; died on 29 Dec 1959; was buried in Montrose, Lee, IA.
2. Thomas W. Holmes was born on 27 Nov 1891 in Montrose, Lee, IA; died on 14 Mar 1958; was buried in Ft. Madison, Lee, IA.
3. George Wilson Holmes was born on 28 Oct 1883 in Montrose, Lee, IA; died in Jun 1965; was buried in Keokuk, Lee, IA.
4. Jessie Edward "Jess" Holmes was born on 17 Aug 1885 in Montrose, Lee, IA; died on 10 Jul 1961 in Donnellson, Lee, IA; was buried in Ft. Madison, Lee, IA.
5. Sidney Vermillion Holmes was born on 2 Mar 1897 in Montrose, Lee, IA; died on 15 Sep 1981 in Fairfield, Jefferson, IA; was buried in Donnellson, Lee, IA.
6. Nellie Mae Holmes was born on 18 Dec 1888 in Montrose, Lee, IA; died on 1 Apr 1963.